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Getting rid of unused medicines safely

Take unused medicines to a drug take-back location or mail them back, flush only those on the FDA flush list, and trash the rest mixed with dirt or coffee grounds.

Satisfy+ Editorial · Published June 1, 2026 · 3 min read · 20 min to do

Dozens of empty orange prescription pill bottles with white caps scattered on a white surface
ToastedPictures / Envato

At a glance

Best
A drug take-back location or a mail-back envelope
Next
Flush, only if it's on the FDA flush list
Otherwise
The trash, mixed with dirt, cat litter or coffee grounds
Every time
Scratch personal information off the labels

Unused and expired medicines turn up in bathrooms, kitchens, bedrooms and purses. They're a risk if someone takes a medicine prescribed for another person, or if a child or pet swallows one. A take-back option is the best way to get rid of most prescription and over-the-counter medicines, and it destroys everything dropped off. When none is close, the FDA flush list and the household trash cover the rest.

What you need

  • The medicines, in their bottles and packaging
  • A zip-top plastic bag
  • Dirt, cat litter or used coffee grounds
  • A marker, to black out the labels

Steps

  1. 1

    Gather the medicines

    Check every cabinet, drawer, bag and purse for medicines that are expired or no longer used.

    10 min

  2. 2

    Scratch out the personal information

    Black out your name and the prescription details on every bottle label and package.

    5 min

  3. 3

    Take them to a drug take-back location

    Some retail, hospital and clinic pharmacies and law enforcement offices are registered with the Drug Enforcement Administration (DEA) to collect medicines, including controlled substances. They may have a kiosk or a drop-off box.

    30 min

  4. 4

    Or mail them back

    Some pharmacies sell prepaid drug mail-back envelopes, or give them out free. Fill the envelope, seal it and mail it through the U.S. Postal Service.

    5 min

  5. 5

    Flush only what's on the flush list

    If there's no take-back option, check the FDA flush list. It covers medicines with misuse potential that can kill with a single dose taken by the wrong person, such as those containing fentanyl, oxycodone, hydrocodone, morphine or methadone. Don't flush anything that isn't on the list.

    2 min

  6. 6

    Put the rest in the trash

    Take the medicines out of their containers and mix them, without crushing tablets or capsules, with dirt, cat litter or used coffee grounds. Seal the mixture in a plastic bag and put it in the household trash. Throw out or recycle the empty bottles.

    5 min

Clear out unused medicines

  • Go through every cabinet and bag for expired medicines
  • Find the nearest drug take-back location
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Take-back days and special cases

The DEA hosts National Prescription Drug Take-Back Days from time to time, with temporary drop-off sites in communities across the country. Local law enforcement sometimes holds its own events, and the local waste authority can tell you about others nearby.

If a doctor or pharmacist gave you disposal instructions for a medicine, follow them. Sprays, lozenges and other unusual forms can have their own instructions in the package insert or medication guide.

Why some medicines get flushed

The medicines on the flush list are dangerous enough that a single accidental dose can kill a child, an adult or a pet. Flushing them when no take-back option is close keeps them from being found, touched or misused. The FDA studied the active ingredients on the list and found they pose negligible risk to the environment.

FAQ

What's the best way to get rid of old medicines?

Take them to a drug take-back location, often at a pharmacy or police station, or use a prepaid mail-back envelope.

Can I flush old pills down the toilet?

Only if they're on the FDA flush list and no take-back option is available.

How do I throw medicine in the trash?

Mix it with dirt, cat litter or used coffee grounds, seal it in a plastic bag and put it in the trash. Don't crush the pills.

Sources

Checked October 20, 2026

  1. U.S. Food and Drug Administration. Disposal of unused medicines: what you should know (2024)
  2. U.S. Food and Drug Administration. Drug disposal: drug take-back options (2024)
  3. U.S. Food and Drug Administration. Drug disposal: FDA's flush list for certain medicines (2024)
  4. U.S. Food and Drug Administration. Drug disposal: dispose of non-flush list medicine in trash (2024)
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